Research Specifications
- Full Name:
- Nicotinamide adenine dinucleotide (oxidised form)
- CAS Number:
- 53-84-9
- Molecular Weight:
- 663.43 Da
- Form:
- Lyophilized powder
- Purity:
- ≥98% (HPLC verified)
- Storage:
- −20°C; protect from moisture and light
- Reconstitution:
- Sterile saline or bacteriostatic water
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Electron Transfer, Sirtuin Activation & DNA Repair Substrate
NAD+ (nicotinamide adenine dinucleotide, CAS: 53-84-9) is a dinucleotide consisting of adenosine monophosphate linked to nicotinamide mononucleotide via a pyrophosphate bond. It cycles between oxidized (NAD+) and reduced (NADH) forms as it accepts and donates electrons in oxidative phosphorylation, glycolysis, and the TCA cycle. Beyond its role as a redox carrier, NAD+ is a consumed substrate for three longevity-associated enzyme classes: Sirtuins (SIRT1-7) — NAD+-dependent deacylases regulating chromatin remodeling, mitochondrial biogenesis via PGC-1α, stress resistance, and inflammation; PARPs (poly ADP-ribose polymerases) — DNA damage repair enzymes; and CD38/CD157 — NAD+ glycohydrolases involved in calcium signaling. NAD+ levels decline approximately 50% between ages 20 and 60 due to increased PARP activity from accumulating DNA damage, increased CD38 expression, and decreased biosynthesis. Molecular weight: 663.43 Da.
What ships on this SKU
Lyophilized NAD+ (oxidised nicotinamide adenine dinucleotide) 500mg net weight per vial. CAS 53-84-9 and molecular weight 663.43 Da on the label and lot CoA.
Purity line on the CoA
Listed at ≥98% HPLC. NAD+ is hygroscopic — keep the cap sealed until you reconstitute; lot-matched CoA ships from the supplier on qualifying orders.
Storage printed with the goods
Lyophilized: −20°C, protect from moisture and light. Reconstitute with sterile saline or bacteriostatic water per your SOP; use solution within the supplier window on your CoA (typically two to four weeks).
NAD+ 500mg Shipping & Delivery
US Shipping: 3–5 Business Days
NAD+ 500mg ships tracked from a US fulfillment center. Free shipping on orders $200+; flat-rate $14.95 under.
Cold-Chain & Packaging
Lyophilized NAD+ 500mg is heat-stable in transit. Vials ship in rigid cold-pack mailers with lot-matched CoA included.
Storage on Arrival
Refrigerate unopened lyophilized vials at 2–8°C. Reconstitute only when ready to use; refer to the per-compound protocol guide.
Purity Verified on Every Lot
Every NAD+ 500mg vial ships with a lot-matched Certificate of Analysis confirming ≥98% purity via HPLC. Requests for raw chromatograms accepted post-purchase.
NAD+ 500mg
$65.00